{"id":41,"date":"2017-05-09T14:55:34","date_gmt":"2017-05-09T05:55:34","guid":{"rendered":"http:\/\/iddd.brc.riken.jp\/en\/?page_id=41"},"modified":"2025-06-06T10:07:09","modified_gmt":"2025-06-06T01:07:09","slug":"top","status":"publish","type":"page","link":"http:\/\/iddd.brc.riken.jp\/en\/","title":{"rendered":"top"},"content":{"rendered":"<p style=\"float:right;margin-right: 20px;height: 70px;\"><a href=\"\/\/iddd.brc.riken.jp\/ja\/\"><img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/ja_logo.png\" alt=\"japanese\"><\/a><\/p>\n<div style=\"clear: both;\"><\/div>\n<div style=\"width: 780px; height: 1400px;\">\n<p style=\"width: 101px; height: 100px; float: left; text-align: center; \">\n  <img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/iddd_logo.png\" alt=\"iPSC-based Drug Discovery and Development Team\"\/><\/p>\n<p style=\"height: 65px; padding-top: 30px;\"><span style=\"font-size: 30px;\">&nbsp;iPSC-based Drug Discovery and Development Team<\/span><\/p>\n<p style=\"text-align: right;\">Team Leader \u00a0<span style=\"font-size: x-large;\">Haruhisa INOUE, M.D.,Ph.D.<\/span><\/p>\n<p>  <img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/iddd1.png\" alt=\"Research Outline\" \/><\/p>\n<div style=\"text-align: left; margin: 0px; padding: 0px; height: 450px;\"><img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/iddd4.png\" alt=\"iddd4\" \/><span style=\"color: #171c61; font-size: X-large; font-weight: bold; vertical-align: bottom;\">Disease modeling and drug discovery using disease-specific iPS cells in RIKEN BRC cell bank<\/span><\/p>\n<div style=\"width: 413px; float: left; text-align: center; position: relative;\">\n<p style=\"font-size: large; font-weight: bolder; text-align: left; line-height: 120%; margin: 0px; padding: 0px;\">\n      <img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/iddd2.png\" alt=\"STEP1\" \/><br \/>\n      Ref:Inoue et al., The EMBO Journal,2014<\/p>\n<p style=\"font-size: large; font-weight: bolder; text-align: left; line-height: 120%; margin: 10px 0px 0px; padding: 0px;\">Induction of various types of cells from patient iPS cell<\/p>\n<p style=\"height:20px;\">\n<p style=\"background-color: #cccccc; margin: 30px 30px 0px; padding: 30px 30px 0px; font-size: large; font-weight: bolder; line-height: 120%; text-align: left;\">Accelerate open innovation for drug discovery in collaboration with outside partners<\/p>\n<p style=\"background-color: #cccccc; margin: 0px 30px 30px; padding: 20px 30px 30px; font-size: large; font-weight: bolder; line-height: 120%; text-align: left;\">Back up RIKEN BRC cell bank in emergency<\/p>\n<\/p><\/div>\n<div style=\"width: 350px; float: right; text-align: center; position: relative;\">\n<p style=\"font-size: large; font-weight: bolder; text-align: left; line-height: 120%;\">\n      <img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/iddd3.png\" alt=\"STEP2\" \/><br \/>\n      Recapitulate and Verify disease phenotypes<br \/>Develop cellular-level disease phenotypes<\/p>\n<p style=\"height:20px;\">\n<p style=\"font-size: large; font-weight: bolder; text-align: left; line-height: 120%;\">\n      <img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/images\/iddd5.png\" alt=\"STEP3\" \/><br \/>\n      Evaluate potential drugs using patient cells<\/p>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp;iPSC-based Drug Discovery and Development Team Team Leader \u00a0Haruhisa INOUE, M.D.,Ph.D. Disease modeling  [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-41","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/41","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=41"}],"version-history":[{"count":22,"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/41\/revisions"}],"predecessor-version":[{"id":271,"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/41\/revisions\/271"}],"wp:attachment":[{"href":"http:\/\/iddd.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=41"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}