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iPSC-based Drug Discovery and Development Team

 iPSC-based Drug Discovery and Development Team

Team Leader  Haruhisa INOUE, M.D.,Ph.D.

Research Outline

iddd4Disease modeling and drug discovery using disease-specific iPS cells in RIKEN BRC cell bank

STEP1
Ref:Inoue et al., The EMBO Journal,2014

Induction of various types of cells from patient iPS cell

Accelerate open innovation for drug discovery in collaboration with outside partners

Back up RIKEN BRC cell bank in emergency

STEP2
Recapitulate and Verify disease phenotypes
Develop cellular-level disease phenotypes

STEP3
Evaluate potential drugs using patient cells